4th Alliance4Life Meeting in Latvia

Almost 100 representatives from ten research centres and universities from nine Central and Eastern European (CEE) countries met for the fourth time at the Alliance4Life meeting in early June. These partners form a unique community of institutions in the life sciences and medical fields that is unparalleled in the region. The focus of the meeting was to share best practices and receive training from internal and external experts, as well as discuss the future of the alliance.

The Latvian seaside resort of Jūrmala was the centre of lively discussions held over several days, aimed at sharing ideas for achieving qualitative changes in the management of institutions, thus creating more favourable conditions for high-quality research in life sciences. The Latvian Institute of Organic Synthesis (LIOS), one of the Alliance4life members, was the host of the event.

Both experts from the member institutions and invited lecturers from outside of the alliance were involved in sharing best practices through lectures and training sessions in the plenary sessions. The agenda of the Steering Committee meetings and the Strategy Board focused on planning the alliance’s future strategy and activities, particularly from 2020. Several decisions were made, such as achieving greater involvement of researchers in project-based collaboration, building greater capacity for shaping European research policy, and strengthening collaborations with other EU networks. A draft of a White Paper with specific recommendations for policymakers at the national and European levels was also discussed.

The alliance was created as a joint project that received support from the Horizon 2020 European Framework Program for Research and Innovation. “It is certainly positive that the alliance, thanks to its intensive joint work, has turned into a real association over the last two years. This is evidenced by the draft Memorandum of Understanding that is foreseen to be signed at the next meeting in Vilnius in October, thus establishing the Alliance4Life as a permanent structure,” explained Zlatuše Novotná, Head of Strategic Partnerships and International Relations at CEITEC MU and Alliance4Life Coordinator.

 “We have succeeded in creating a platform based on the discussion of focus groups working on the most pressing topics relevant to every CEE research institution –  scientific strategy and research evaluation, grants, institutional management, technology transfer, human resources and training, and PR and communication,” said Jiří Nantl, Director of CEITEC MU.

10-12June_2019_Liga Lejiņa, State Secretary of the Ministry of Education and Science of the Republic of Latvia
Opening speech by Liga Lejiņa, State Secretary of the Ministry of Education and Science, Republic of Latvia

Opening speech by Osvalds Pugovičs, Director of LIOS
Opening speech by Osvalds Pugovičs, Director of LIOS

10-12June_2019_Opening speech by Jiří Nantl, Chair of Strategy Board and Director of CEITEC Masaryk UniversityOpening speech by Jiří Nantl, Chair of Strategy Board and Director of CEITEC Masaryk University

10-12June_2019_Plenary session during J. Nantl's speechPlenary session

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All4Life Alliance4Life research centres and universities have been working together since 2018 to improve their functions as a whole, including the internal cultures of their scientific worksites, management quality, and personnel policy rules. In the Alliance4Life, Latvia is represented by LIOS.

New approaches for synthesis of cyclohexanediones and 2-oxa-6-azabicyclo[2.2.2]octanes


Symposium “Physiopathology of sigma-1 (σ1) receptors”

From May 31 to June 2 (2019) the second European symposium “Physiopathology of sigma-1 (σ1) receptors” took place at the Latvian Institute of Organic Synthesis.

Researchers from 12 countries shared their knowledge and research on Sigma1 receptors and discussed possible areas for future cooperation.




INNOCENT project meeting in Riga

M-era.Net project INNOCENT 3rd Partner meeting took place at Latvian Institute of Organic Synthesis from Monday, April 15 – Tuesday, April 16, 2019.

The objective of this meeting was to discuss the progress and detailed plans of individual research groups for the final 6 month period and to discuss possibility of project extension.


Learn more about INNOCENT project!

Great collaboration within the COST action

Collaboration within the COST action CA16112 “Personalized Nutrition in aging society: redox control of major age-related diseases”  has resulted in the publication in the open access journal Nutrients (IF 4.196):

Tess De Bruyne, Bieke Steenput, Lynn Roth , Guido R. Y. De Meyer, Claudia Nunes dos Santos, Kateřina Valentová, Maija Dambrova, Nina Hermans.
Dietary Polyphenols Targeting Arterial Stiffness: Interplay of Contributing Mechanisms and Gut Microbiome-Related Metabolism.Nutrients 2019, 11(3), 578; doi:10.3390/nu11030578


INNOCENT project findings in the design of nanoparticle delivery materials

Journal Pharmaceutics (IF = 3.746) published a research paper from EuroNanoMed2 project “Innovative nanopharmaceuticals: targeting breast cancer stem cells by a novel combination of epigenetic and anticancer drugs with gene therapy” (INNOCENT):

Martins Rucins, Pavels Dimitrijevs, Klavs Pajuste, Oksana Petrichenko, Ludmila Jackevica, Anita Gulbe, Signe Kibilda, Krisjanis Smits, Mara Plotniece, Dace Tirzite, Karlis Pajuste, Arkadij Sobolev, Janis Liepins, Ilona Domracheva, Aiva Plotniece. Contribution of Molecular Structure to Self-Assembling and Biological Properties of Bifunctional Lipid-Like 4-(N-Alkylpyridinium)-1,4-Dihydropyridines. Pharmaceutics 2019, 11(3), 115.