Dr. Nadia Pikun (Laboratory of Membrane Active Compounds and β-diketones ), while continuing studies of fluorine chemistry within her PostDoc project, spent 3 months in

According to the decision of the President of Latvia, Egils Levits, and the Chapter of Orders on 30th October 2020, the Chairman of the LIOS

Full-time postdoctoral scholar position in confocal microscopy and histology is open in the Pre-clinical Biomaterial Evaluation group. Requirements and additional information: https://www.osi.lv/en/vacancies/ Application deadline 14/12/2020

Research conducted by professor Kristaps Jaudzems group (LIOS) and researchers from Latvian Biomedical Research and Study Centre has been published in the journal “Pathogens” (IF 

Joint research done by professor Ivars Kalviņš (LIOS) and scientists from Poland on a new target for anti-metastatic treatment has been published in the journal

As of September 2020, the Latvian Institute of Organic Synthesis (LIOS) has started the implementation of a 3-year project Springboard for excellence in advanced development

Journal Pharmacopsychiatry (IF=4.340, 2019) has published a joint article on the safety and tolerability of phenibut from the Laboratory of Pharmaceutical Pharmacology (LIOS), Riga Stradins

Our young researchers under Janis Veliks supervision have published a case study which showed that fluorocyclopropane analogue of the anticancer drug cabozantinib shows improved selectivity

Scientists from the Laboratory of Pharmaceutical Pharmacology & Laboratory of Physical Organic Chemistry have published studies of metformin, the most widely prescribed oral medication for

Liene Grigorjeva (Organic Synthesis Methodology Group) has published a review article in the journal “Organic & Biomolecular Chemistry” (IF=3.490, 2019). This review summarizes the C–H

Open Access journal Catalysts (IF = 3.520) has published joint review article from the Laboratory of Membrane Active Compounds and β-diketones (LIOS), State Research Institute

Continuing studies of electrophilic fluorination of heterocycles, Dr. Nadia Pikun with her colleagues from the Laboratory of Membrane Active Compounds and β-diketones has elaborated  a

We are proud to announce that our journal “Chemistry of Heterocyclic Compounds” has increased its impact factor and reach 1.519.         For

Continuing studies on eleganine A total synthesis, Dr. Smits (Laboratory of CNS Active Compounds) and Dr. Zemribo elaborated a new synthetic approach towards the core

On 29 June, President of Latvia Egils Levits visited the Latvian Institute of Organic Synthesis (LIOS) to receive Solomon Hiller Medal, an award honouring scientific

Research against resistance to β-lactam antibacterials by Dr. Trapencieris group and colleagues from the University of Oxford, University of Leeds and Jacobs University Bremen has

Dr. Dace Rasiņa et.al. (Organic Synthesis Methodology group) have published a concise bioinspired semisynthesis of rumphellaones A–C and their C-8 epimers from β-caryophyllene in the

Dr. Pavel Arsenyan group elaborated a fast and convenient methodology for the preparation of 10-nonyl acridine orange (NAO) and its silyl analogues to improve their

Researchers from the Laboratory of Pharmaceutical Pharmacology have shown that empagliflozin treatment preserves mitochondrial fatty acid oxidation in the heart under conditions of chronic lipid

Full-time Postdoctoral positions in structural biology and molecular biology are open in the Biotechnology group. Requirements and additional information: for Postdoctoral student in molecular biology

Continuing studies of carbonic anhydrase (CA) inhibitors, professors Raivis Žalubovskis’ (LIOS) and Claudiu T. Supuran’s groups showed that clinically used antibiotic Furagin and its derivatives

Dr. Domracheva et.al. have published studies about novel 4-pyridinio-1,4-dihydropyridine (1,4-DHP) derivatives possessing calcium channel modulating activity.  The antagonist, agonist, and dual-action effect of the 1,4-DHP

Dr. Grigorjeva et.al. (Organic Synthesis Methodology group) have developed an efficient method for the synthesis of 3-hydroxymethyl isoindolinones via cobalt-catalyzed C(sp2)–H carbonylation of phenylglycinol derivatives using

Dr. Grigorjeva et.al. (Organic Synthesis Methodology group) have developed a new method for cobalt catalyzed C(sp2)-H functionalization of phenylglycinol derivatives with terminal and internal alkynes