New studies on selenocystine peptides

Dr. Pavel Arsenyan group showed a new approach for the generation of selenocysteinyl electrophile by weak Lewis acids or oxidants. The elaborated protocol allows the construction of phenylindeno[1,2‐ c ]chromene moiety in 5‐ endo‐dig /6‐ endo‐dig cascade reactions. This method is published in the European Journal of Organic Chemistry (IF 3.029):

Sindija Lapcinska, Pavel Arsenyan.
Selenocystine peptides performance in 5‐endo‐dig reactions.
Eur. J. Org. Chem., 2020, DOI: 10.1002/ejoc.201901548


The research was supported by Latvian Institute of Organic Synthesis internal student grant IG-2018-06.