New article in the field of natural product synthesis

Dr. Dace Rasiņa (Organic Synthesis Methodology group) have published a concise bioinspired semisynthesis of rumphellaones A–C and their C-8 epimers from β-caryophyllene in the Journal of Natural Products (IF=4.257, 2019).

Stakanovs G., Mishnev A., Rasina D.*, Jirgensons A.
A Concise Bioinspired Semisynthesis of Rumphellaones A–C and Their C-8 Epimers from β-Caryophyllene.  J. Nat. Prod. 2020, doi: 10.1021/acs.jnatprod.0c00403

This is the first semisynthetic route toward rumphellaones B and C and their C-8 epimers as well as the shortest synthesis of rumphellaone A and its C-8 epimer from the most accessible sesquiterpene, β-caryophyllene.