| Acronyme | SMARTPIEZO |
| Website | |
| Call | M-ERA.NET Joint Call 2024 |
| Implementation period | 01.07.2025. – 31.06.2028. |
| Project coordinator | Dr. hab. Dorota Kołbuk-Konieczny |
Project partners
| Institute of Fundamental Technological Research of the Polish Academy of Sciences (IPPT PAN, Warsaw, Poland) |
| Scinnovation s.r.o. (Prague, Czech Republic) | |
| Innovative Medicine Centre, (IMC, Vilnius, Lithuania) | |
| Latvian Institute of Organic Synthesis (LIOS, Riga, Latvia) | |
| Leader of Latvian team | Dr. Arkadijs Sobolevs |
| Total costs | € 1 232 953, Total requested funding: € 1 105 203 |
| Costs for Latvian partner | € 300 000 |
Summary
Needs: Joint defects (JD) from trauma, osteoarthritis, arthritis, or cancer represent a major challenge in healthcare due to poor treatment options and limited regeneration.
Objectives: Project aims to develop a bio-based, piezoelectric osteochondral construct sPiezoBio for JD repair and drug testing. The primary objectives are: to develop piezoelectric and bio-based materials; design two osteochondral repair products; overcome current limitations in JD repair materials by creating multifunctional, biomimetic constructs; enhance osteogenesis and chondrogenesis through ultrasound and mechanical stimulation.
Applications: The sPiezoBio can be applied in JD treatment, offering solutions for JD filling. They will also serve as in-vitro osteochondral tissue models for drug and treatment testing.
Impact&Benefits: sPiezoBio.