Studies prove the application of high‐sensitivity MAS NMR in vaccine design and formulation

Joint research on the structural analysis of an antigen chemically‐coupled on virus‐like particles by Kristaps Jaudzems (IOS, Laboratory of Physical Organic Chemistry) and scientists from the Université de Lyon, the Aix-Marseille Université and Latvian Biomedical Research and Study Centre has been published in the leading chemistry journal –  Angewandte Chemie (IF=12.959).

In this study, the authors demonstrate that high‐sensitivity magic‐angle spinning (MAS) solid‐state NMR can play a major role in vaccine design, formulation studies and manufacturing process development.

Read the article:

Jaudzems, K.*; Kirsteina, A.; Schubeis, T.; Ouari, O.; Bogans, J.; Kazaks, A.; Tars, K.; Lesage, A.*; Pintacuda, A.*
Structural Analysis of an Antigen Chemically‐Coupled on Virus‐Like Particles in Vaccine Formulation.
Angew. Chem. Int. Ed., 2021. DOI: 10.1002/anie.202013189