Published Research on the Role of Protein Disulphide Isomerase A1 in Breast Cancer

Joint research done by professor Ivars Kalviņš (LIOS) and scientists from Poland on a new target for anti-metastatic treatment has been published in the journal “Cancers” (IF  6.126, 2019).  Studies showed that protein disulphide isomerase A1 is involved in the regulation of breast cancer cell adhesion and transmigration via lung microvascular endothelial cells.

Stojak, M.; Milczarek, M.; Kurpinska, A.; Suraj-Prazmowska, J.; Kaczara, P.; Wojnar-Lason, K.; Banach, J.; Stachowicz-Suhs, M.; Rossowska, J.; Kalviņš, I.; Wietrzyk, J.; Chlopicki, S.
Protein Disulphide Isomerase A1 Is Involved in the Regulation of Breast Cancer Cell Adhesion and Transmigration via Lung Microvascular Endothelial Cells.
Cancers 2020, 12, 2850, doi: 10.3390/cancers12102850

The research was financed by The National Centre for Research and Development of Poland (STRATEGMED1/233226/11/NCBR/2015) was partially by Latvian National Fundamental and Applied Research (Grant No. lzp-2018/1-0143).