Molecular self-association mechanism studies conducted by researchers from the Nuclear Magnetic Resonance Group (LIOS) and Matteo Salvalaglio from the Thomas Young Centre (University College London)
Scientists from the Pharmacomodulators Synthesis group & Laboratory of Pharmaceutical Pharmacology have reported that isoselenazolium salts may be a promising platform for the development of
The review article on cobalt-catalyzed carbonylation of the C–H bond by Liene Grigorjeva and Lūkass T. Lukasevics (Organic Synthesis Methodology Group) has been chosen by
A review article on new strategies and future nanomedicine perspectives in breast cancer therapy has been published in the journal “Cancers” (IF 6.126, 2019). This
Dr. Nadia Pikun (Laboratory of Membrane Active Compounds and β-diketones ), while continuing studies of fluorine chemistry within her PostDoc project, spent 3 months in
According to the decision of the President of Latvia, Egils Levits, and the Chapter of Orders on 30th October 2020, the Chairman of the LIOS
Full-time postdoctoral scholar position in confocal microscopy and histology is open in the Pre-clinical Biomaterial Evaluation group. Requirements and additional information: https://old.osi.lv/en/vacancies/ Application deadline 14/12/2020
Research conducted by professor Kristaps Jaudzems group (LIOS) and researchers from Latvian Biomedical Research and Study Centre has been published in the journal “Pathogens” (IF
Joint research done by professor Ivars Kalviņš (LIOS) and scientists from Poland on a new target for anti-metastatic treatment has been published in the journal
As of September 2020, the Latvian Institute of Organic Synthesis (LIOS) has started the implementation of a 3-year project Springboard for excellence in advanced development
Journal Pharmacopsychiatry (IF=4.340, 2019) has published a joint article on the safety and tolerability of phenibut from the Laboratory of Pharmaceutical Pharmacology (LIOS), Riga Stradins
Our young researchers under Janis Veliks supervision have published a case study which showed that fluorocyclopropane analogue of the anticancer drug cabozantinib shows improved selectivity
Scientists from the Laboratory of Pharmaceutical Pharmacology & Laboratory of Physical Organic Chemistry have published studies of metformin, the most widely prescribed oral medication for
Liene Grigorjeva (Organic Synthesis Methodology Group) has published a review article in the journal “Organic & Biomolecular Chemistry” (IF=3.490, 2019). This review summarizes the C–H
Open Access journal Catalysts (IF = 3.520) has published joint review article from the Laboratory of Membrane Active Compounds and β-diketones (LIOS), State Research Institute
Continuing studies of electrophilic fluorination of heterocycles, Dr. Nadia Pikun with her colleagues from the Laboratory of Membrane Active Compounds and β-diketones has elaborated a
We are proud to announce that our journal “Chemistry of Heterocyclic Compounds” has increased its impact factor and reach 1.519. For
Continuing studies on eleganine A total synthesis, Dr. Smits (Laboratory of CNS Active Compounds) and Dr. Zemribo elaborated a new synthetic approach towards the core
On 29 June, President of Latvia Egils Levits visited the Latvian Institute of Organic Synthesis (LIOS) to receive Solomon Hiller Medal, an award honouring scientific
Research against resistance to β-lactam antibacterials by Dr. Trapencieris group and colleagues from the University of Oxford, University of Leeds, and Jacobs University Bremen has
Dr. Dace Rasiņa et.al. (Organic Synthesis Methodology group) have published a concise bioinspired semisynthesis of rumphellaones A–C and their C-8 epimers from β-caryophyllene in the
Dr. Pavel Arsenyan group elaborated a fast and convenient methodology for the preparation of 10-nonyl acridine orange (NAO) and its silyl analogues to improve their
Researchers from the Laboratory of Pharmaceutical Pharmacology have shown that empagliflozin treatment preserves mitochondrial fatty acid oxidation in the heart under conditions of chronic lipid
Full-time Postdoctoral positions in structural biology and molecular biology are open in the Biotechnology group. Requirements and additional information: for Postdoctoral student in molecular biology