The new A4L_ACTIONS project just started The kick-off conference of the H2020 project A4L_ACTIONS, connecting thirteen members from the strategic partnership called Alliance4Life, took place
EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from
Researchers at the Organic Synthesis Methodology Group (Latvian Institute of Organic Synthesis) and the Francis Crick Institute have designed potential drug-like compounds which effectively block
A straightforward and atom‐economic method for the functionalization of short selenocystine‐containing peptides proposed by researchers from the Pharmacomodulators Synthesis Group (LIOS) has been published in
The stereoselective total synthesis of the proposed structure of a potent serotonin 5-HT1A receptor agonist uncarialin A elaborated by LIOS scientists have been published in
Joint research on the electrosynthesis of hypervalent bromine by Edgars Suna and Igors Sokolovs (IOS, Laboratory of Advanced Technologies for Organic Synthesis) and scientists from
A review article on isolation, chemistry, and biology of pyrrolo[1,4]benzodiazepine natural products by Gints Smits group (Laboratory of CNS Active Compounds) has been published in
Prof. Kristaps Jaudzems (IOS, Laboratory of Physical Organic Chemistry) has given a lecture on artificial spider silk at the largest deep tech industry event in
Researchers from the Pharmacomodulators Synthesis Group (LIOS) have demonstrated a convenient one-pot process for the construction of selanyl and tellanyl substituted N-polyaromatic systems (up to
Joint research on the structural analysis of an antigen chemically‐coupled on virus‐like particles by Kristaps Jaudzems (IOS, Laboratory of Physical Organic Chemistry) and scientists from
Continuing studies of cobalt-catalyzed C(sp2)–H carbonylation reactions Liene Grigorjeva et al. (Organic Synthesis Methodology group) have reported an efficient protocol for the synthesis of 1,2-dihydroisoquinolinone
Janis Veliks et al. (Organic Synthesis Methodology group) have reported a new strategy of synthesizing monofluorinated five-membered rings via fluoromethylene transfer. This approach has been published
Joint research by Pavel Arenyan group (IOS) and scientists from the Kaunas University of Technology on new OLEDs has been published in the Journal of
Joint research done by scientists from the Laboratory of Membrane Active Compounds and β-diketones (IOS) and the University of Latvia on physicochemical properties of amphiphilic
A researcher group from LIOS has proposed a very simple method for a fast determination of NMR yield in the organic synthesis lab by determining
Researchers led by Professor Zhang (US) have reported that BBOX1 is a potential therapeutic target in triple negative breast cancer. Effective BBOX1 inhibitors for the
Scientists from the Laboratory of Pharmaceutical Pharmacology (LIOS) in collaboration with colleges from COST Action “EU‐CARDIOPROTECTION” in their latest review article explores the mechanisms of
Continuing studies of the properties and reactivity of fluoromethylsulfonium salts Janis Veliks et al. (Organic Synthesis Methodology group) has reported redesigned reagents for fluoromethylene transfer
Alliance4Life’s new project A4L_ACTIONS, submitted under the Horizon 2020 programme, has been selected for funding. Alliance4Life’s next three years will thus be co-financed with a
In their latest publication researchers at the Laboratory of Pharmaceutical Pharmacology (LIOS) have demonstrated that microbiota-derived metabolite trimethylamine N-oxide (TMAO) protects mitochondrial energy metabolism and cardiac
Scientists from Biotechnology group (LIOS) in collaboration with Biomolecular Engineering Laboratory (Politecnico di Milano, Italy) have engineered a novel enzyme to improve the speed and
Researchers at the Laboratory of Pharmaceutical Pharmacology (LIOS) in their latest publication have demonstrated that sigma-1 receptor (Sig1R) is a valuable target for the development
Multiple biological properties of self-assembling synthetic lipids studied by researchers from the Laboratory of Membrane Active Compounds and β-diketones (LIOS) have been published in the
Prunus padus L. has been traditionally used in European ethnomedicine as a treatment for internal and external purposes and is mainly used to reduce inflammation,