The review article by scientists from the Biotechnology group (Latvian Institute of Organic Synthesis) and European Institute of Oncology (Italy) on recent experimental and computational

Researchers at the Laboratory of Pharmaceutical Pharmacology (Latvian Institute of Organic Synthesis) and Riga Stradiņš University (Latvia) have shown for the first time that fasting-mimicking

Researchers from the Latvian Institute of Organic Synthesis, Institute for Environmental Solutions (Latvia) and SIA “Field and Forest” (Latvia) have shown for the first time

On 20th and 21st of January 2022 Alliance4Life_ACTIONS hosted its first Trigger Event targeting knowledge transfer professionals and early-stage researchers. Due to the current pandemic

Tetrazole is a motif of several marketed drugs and is an important substructure for the discovery of new drug candidates. This motivates the development of

Researchers at the Latvian Institute of Organic Synthesis and Rigas Stradins University in their latest study, published in the International Journal of Molecular Sciences (IF

A novel target for cardioprotective therapies – enzyme N6-trimethyllysine dioxygenase (TMLD) – has been identified by researchers from the Latvian Institute of Organic Synthesis (LIOS),

Together with partners from the ENABLE project consortium, researchers at the Latvian Institute of Organic Synthesis for the first time present results that prove the

Researchers in the Biotechnology group of the Latvian Institute of Organic Synthesis, at the University of Granada (Spain) and the Institute of Parasitology and Biomedicine

From October 28 to 29, the 12th Paul Walden Symposium took place virtually. The Paul Walden Symposium on Organic Chemistry has become a tradition. It

A multi-target approach in drug discovery is a promising approach in drug discovery. It is the opposite of the traditional path and paradigm of ligand-receptor

The review article summarizing the current progress, challenges and future perspectives on C–H bond functionalization by high-valent cobalt catalysis by Liene Grigorjeva’s group (Organic Synthesis

Greater celandine (Chelidonium majus L.) is a widely distributed valuable medicinal plant. In traditional medicine, this plant has been used to treat bile and liver

The review by scientists from the Latvian Institute of Organic Synthesis and Department of Regenerative Medicine of State Research Institute Centre for Innovative Medicine (Vilnius,

Researchers at the Latvian Institute of Organic Synthesis (Pharmacomodulators synthesis group) have developed a method for cardiolipin (CL) quantitative analysis and therefore have highlighted using

Researchers at the Laboratory of Pharmaceutical Pharmacology (Latvian Institute of Organic Synthesis) have proposed a novel pharmacological approach to increase levels of polyunsaturated fatty acids.

Researchers from groups led by Dr. Emilio Parisini (LIOS, Biotechnology group) and Dr. Olga Bruno have designed, synthesized, and performed the biological evaluation and structural

Enantiopure secondary alcohols are valuable intermediates in medicinal chemistry since many marketed drugs such as crizotinib, lorlatinib, cenobamate, atomoxetine, and duloxetine are derivatives of chiral

Propylamycin is a next-generation aminoglycoside antibiotic that displays increased antibacterial potency. But due to the hydroxy group in propylamycin 5′′-position, it is inactivated by aminoglycoside

Researcher group from Latvian Institute of Organic Synthesis have investigated the molecular mechanisms of cellular insulin resistance. They discovered that long-chain acylcarnitines decrease phosphorylation of

The Covid-19 pandemic is one of the greatest challenges modern medicine has ever faced. While repurposing studies of existing drugs haven’t shown very promising results,