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Conferences
61Ošiņa K.; Germini D.; Botha S.; Vassetzky Y.; Sjakste T.; Sjakste N. 1,4-dihydropyridine derivatives decrease Tat induced γH2AX expression in B lymphocytes. 74th Conference of the University of Latvia, Riga, 2016; 49.      

62Rostoka E ; Ošiņa K.; Isajevs S.; Bisenieks E.; Sjakste N. Jaunu 1,4-DHP atvasinājumu DNS molekulas integritāti pasargājošo un antioksidatīvo īpašību izvērtējums 1. tipa cukura diabēta apstākļos žurkās. Latvijas Universitātes 74. konference, Rīga, 2016; 61.      

63Sjakste N.; Leonova E.; Baumane L.; Rostoka E. DNA binding properties of a series of novel derivatives of 1,4-dihydropyridine. International Conference on Environmental and ocuupational Health ICOETOX; Porto, June 20-24, 2016; 82.      

64Rostoka E ; Baumane L.; Isajevs S.; Sjakste N. Modification of NO production and NOS expression by polyphenols. 6th Global Summit on Medicinal and Aromatic Plants; Riga, Latvia, May 23-26, 2016.      

65Ošiņa K.; Rostoka E ; Sjakste T.; Sjakste N. Psma6 gene expression is affected by 1,4-dihydropyridine derivatives in rat kidneys and blood in streptozotocin induced diabetes mellitus. Abstracts of the 58th International scientific conference of Daugavpils University; Daugavpils Universitātes Akadēmiskais apgāds “Saule”, 2016; 99.      

66Leonova E.; Rostoka E.; Saivaigo S.; Baumane L.; Borisivs V.; Sada Bou; Bisenieks E.; Vassetzky Y.; Duburs G.; Sjakste N. Oxidative stress reduction and DNA repair enhancement by 1,4-dihydropiridine AV-153. Abstracts of the 58th International scientific conference of Daugavpils University; Daugavpils Universitātes Akadēmiskais apgāds “Saule”, 2016; 98.      

67Sokolovska J.; Paramonova N.; Sjakste N.; Sjakste T. Genetic variations in the PSMA3, PSMA6 and PSMC6 genes are associated with type 1 diabetes in Latvians. Latvijas Universitātes 74. konference; Rīga, Latvija, 2016; 63.      

68Romanchikova N.; Strods A.; Strazdina J.; Strumfs B.; Trapencieris P. Study of Novel Aziridine-Based Brutonis Tyrosine Kinase Inhibitor in Mantle Cell Lymphoma. IARC50, France, Lyon, June 7-10, 2016.      

69Valtenbergs O.; Zarins A.; Kizane G.; Supe A.; Baumane L. Radiolysis of lithium orthosilicate pebbles with addition of titanium dioxide. 59th International Conference for Students of Physics and Natural Sciences; Lithuania, Vilnius, March 15-18, 2016; 217.      

70Zarins A.; Kizane G.; Supe A.; Valtenbergs O.; Tamulevičius S.; Andrulevičius M.; Pajuste E.; Rudovica V.; Baumane L.; Kolb M.H.H.; Leys O.; Knitter R. Characterisation and radiolysis of modified lithium orthosilicate pebbles with addition of noble metals. 29th Symposium on Fusion Technolgy (SOFT 2016); Czech Republic, Prague, September 5-9, 2016; 612.      

71Volska K.; Liepinsh E.; Makarova E.; Makrecka - Kuka M.; Kuka J.; Dambrova M. Mitochondrial damage imduces by the accumulation of acyl-coenzymes A and acylcarnitines during ischemia. FEBS workshop: Coenzyme A and its derivatives in health and disease; Marseille, France, August 23 – 27, 2016; 51.      

72Makrecka M.; Kuka J.; Volska K.; Makarova E.; Sevostjanovs E.; Dambrova M.; Liepinsh E. Long-chain acylCoAs vs acylcarnitines in mitochondrial bioenergetics: from in vitro to in vivo ( http://www.bioblast.at/index.php/Makrecka-Kuka_2016_Abstract_MitoFit_Science_Camp_2016). MitoFit Science Camp; Kuhtai, Austria, July 7-13, 2016.      

73Makarova E.; Makrecka - Kuka M.; Grīnberga S.; Dambrova M.; Liepinsh E. Accumulation of acylcarnitines is related to insulin resistance in diabetic Db/db and high fat diet-fed mice. FEBS, Molecular basis of human diseases: 50 years anniversary of Spetses summer schools; Spetses, Greece, May 27 – June 1, 2016; 55.      

74Dambrova M.; Volska K.; Makrecka-Kuka M.; Makarova E.; Kuka J.; Vilskersts R.; Liepinsh E. Cardioprotective effects of pharmacologically decreased long-chain acylcarnitine contents in experimental models of myocardial infarction, atherosclerosis, and diabetes. The 7th European Congress of Pharmacology (EPHAR2016); Istanbul, Turkey, June 26-30, 2016; 81.      

75Latkovskis G.; Mazule M.; Bondare L.; Konrade I.; Makarova E.; Hartmane D.; Strele I.; Dambrova M. Trimethylamine-N-oxide level of patients with metabolic syndrome. The 12th Warsaw International Medical Congress; Warsaw, Poland, May 12-15, 2016; 151.      

76Liepinsh E.; Kuka J.; Dambrova M. Long chain acylcarnitines: new target to prevent ischemia-reperfusion induced damage in heart mitochondria. Mitochondrial Medicine: developing new treatments for mitochondrial disease 2016; Hinxton, Cambridge, UK, May 4-6, 2016; 58.      

77Kuka J.; Makrecka - Kuka M.; Liepinsh E.; Dambrova M. Trimethylamine N-oxide impairs substrate oxidation in heart mitochondria. Mitochondrial Medicine: developing new treatments for mitochondrial disease 2016; Hinxton, Cambridge, UK, May 4-6, 2016; 56.      

78Voļska K.; Kūka J.; Makrecka-Kuka M.; Garcia-Mauriño M. Alonso; Dambrova M. Garķēžu acil-karnitīnu nozīme sirds išēmijas-reperfūzijas bojājuma attīstībā. RSU 2016. gada zinātniskā konference, Latvijas iedzīvotāju veselību apdraudošo eksogēno un endogēno faktoru izpēte; Latvija, Rīga, 17. un 18. marts, 2016; 65.      

79Makrecka-Kuka M.; Kūka J.; Voļska K.; Vilšķērsts R.; Bandere D.; Dambrova M. Trimetilamīna N-oksīda ietekme uz mitohondriālo enerģijas metabolismu. RSU 2016. gada zinātniskā konference, Latvijas iedzīvotāju veselību apdraudošo eksogēno un endogēno faktoru izpēte; Rīga, Latvija 17. un 18. marts, 2016; 69.      

80Latkovskis G.; Bondare D.; Mažule M.; Konrāde I.; Makarova E.; Hartmane D.; Strēle I.; Dambrova M. Trimetilamonija oksīda līmenis pacientiem ar metabolisko sindromu. LU 74. zinātniskā konference, Internās medicīnas, kardioloģijas un infektoloģijas sekcija; Rīga, Latvija, 19. februāris, 2016; 79.      

81Makarova E.; Zariņa R.; Muceniece R.; Hartmane D.; Kūka J.; Liepinsh E.; Dambrova M. Plazmas trimetilamīna N-oksīda koncentrācijas novērtēšana eksperimentālajā 2. tipa diabēta modelī. LU 74. zinātniskā konference, Medicīnas bāzes zinātnes un reģeneratīvās medicīnas sekcija; Rīga, Latvija, 19. februāris, 2016; 66.      

82Zvejniece L.; Vavers E.; Svalbe B.; Zvejniece B.; Dambrova M. Neuroprotective effects of R-phenibut in experimental models stroke and neuropathic pain. 9th International Symposium on Neuroprotection and Neurorepair; Leipzig, Germany, April 19 - 22, 2016; 23.      

83Pajuste Kl.; Petricenko O.; Ruciņš M.; Jackevica L.; Plotniece M.; K. Pajuste; Gulbe A.; Plotniece A.; Gosteva M.; Sobolev A.; Domraceva I. Pyridinium derivatives for development of theranostic nanosystems. Abstract of 2nd International Conference “Current Trends in Cancer Theranostics” (CTCT-2016), Druskininkai, Lithuania, June 19-23, 2016; 72.      

84Zvejniece B.; Vāvers E.; Švalbe B.; Dambrova M.; Zvejniece L. R-fenibuta saistīšanās pie lādiņa atkarīgo kalcija jonu kanālu α2–δ subvienības un gabapentīnam līdzīgie pretsāpju efekti. LU 74. zinātniskā konference; Rīga, Latvija, 19. februāris, 2016; 50.      

85Vilskersts R.; Dambrova G.; Mezapuke R.; Bandere D.; Dambrova M. Hlorofilīna un resveratrola vazoprotektīvie efekti hipohlorīta izraisītajā endotēlija disfunkcijas modelī in vitro. RSU zinātniskā konference; Rīga, Latvija, 17.-18. marts, 2016.      

86Mukane L.; Makrecka-Kuka M.; Vavers E. Impact of Sigma-1 receptor ligands on free calcium level during mitochondrial respiration. RSU International Student Conference in Health and Social Sciences; Riga, Latvia, March 16, 2016.      

87Dambrova G.; Mezhapuke R.; Zharkova-Malkova O. ; Bandere D.; Dambrova M. Effects of chlorophyllin and resveratrol on the sodium hypochlorite induced endothelial dysfunction. RSU International Student Conference in Health and Social Sciences; Riga, Latvia, March 16, 2016.      

88Vavers E.; Zvejniece L.; Svalbe B.; Domracheva I.; Vilskersts R.; Makrecka - Kuka M.; Veinberg G.; Dambrova M. Allosteric Sigma-1 receptor modulators: a novel approach to treat memory disorders. FEBS/IUBMB “Molecular basis of human diseases: 50 years anniversary of Spetses summer schools”; Spetses island, Greece. May 27-June 1, 2016; 72.      

89Plotniece A.; Kozlovska T.; Sobolev A.; Gosteva M.; Bandere D.; Plotniece M.; Ose V.; Vigante B.; Petričenko O.; Timofejeva I.; Vezane A.; Pajuste K. Structure-activity relationships of a series of self-assembling compounds on 1,4-dihydropyridine core as delivery agents. In 30th Conference of The European Colloid and Interface Society, ECIS-2016; Rome, Italy. September 4-9, 2016; 527.      

90Upmanis T.; Kreicberga A.; Kazoka H. Investigation of various chromatographic approaches for resolution of foridone and its oxidized form. Book of Abstracts: ISC2016, 31st International Symposium on Chromatography; University College Cork, Ireland. August 28th – September 1st, 2016; 313.      

91Stepanovs D.; Yanichev A.; Balodis M.; Beļakovs Sergejs; Mishnev A.F. Pharmaceutical cocrystals of hydrochlorothiazide: Molecular recognition, crystal structures, and selected physicochemical properties, https://elsevier.conference-services.net/viewsecurePDF.asp?conferenceID=3983&abstractID=917624. , 2016.      

92Apsīte G.; Vigante B.; Timofejeva I.; Vezane A.; Kozlovska T.; Plotniece A.; Rucins M.; Pajuste K.; Sobolev A. Studies of gene delivery activity of aliphatic cationic head group containing 1,4-dihydropyridine. Book of Abstracts, 13th International Conference on Nanosciences & Nanotechnologies (NN16); Thessaloniki, Greece. July 5-8, 2016; 232.      

93*Pajuste K.; Vezane A.; Rucins M.; Gosteva M.; Timofejeva I.; Pajuste Kl.; Petricenko O.; Plotniece M.; Vīgante B.; Kozlovska T.; Sobolev A.; Plotniece A. Structure-activity relationships of a series designed cationic 1,4-dihydropyridines as gene delivery agent. Book of Abstracts, 13th International Conference on Nanosciences & Nanotechnologies (NN16); Thessaloniki, Greece. July 5-8, 2016; 233.      

Theses
94Rasina D. Malārijas aspartilproteināžu inhibitoru izveide. Promocijas darbs ķīmijas zinātņu doktora grāda iegūšanai (Dr.chem.), Rīgas Tehniskā Universitāte, Rīga, 2016.      

95Grandāne A. 1,2-Benzoksatiīn-2,2-dioksīda atvasinājumi un to heterocikliskie analogi kā selektīvi ogļskābes anhidrāžu inhibitori. Promocijas darbs ķīmijas doktora zinātniskā grāda iegūšanai organiskajā ķīmijā (Dr.chem.), Latvijas Universitāte, Rīga, 2016.      

Publications indexed in Scopus database
96*Jaako K.; Waniek A.; Parik K.; Klimaviciusa L.; Aonurm-Helm A.; Noortoots A.; Anier K.; Van Elzen R.; Gerard M.; Lambeir A.-M.; Rossner S.; Morawski M.; Zharkovsky A. Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro. J. Cell Sci. 2016, 129(20), 3792-3802.      

97Rasiņa D.; Lombi A.; Santoro S.; Ferlin F.; *Vaccaro L. Searching for novel reusable biomass-derived solvents: Furfuryl alcohol/water azeotrope as a medium for waste-minimised copper-catalysed azide-alkyne cycloaddition. Green Chem. 2016, 18(23), 6380-6386.      

98Sjakste T.; Paramonova N.; Sjakste N. Structural and functional significance of microsatellites. Bioplym. Cell 2016, 32(5), 334-346.      

99Klosterman J.K.; Veliks J.; Frantz D.K.; Yasui Y.; Loepfe M.; Zysman-Colman E.; Linden A.; *Siegel J.S. Conformations of large macrocycles and ring-in-ring complexes. Org. Chem. Front. 2016, 3(6), 661-666.      

100Veliks J.; Seifert H.M.; Frantz D.K.; Klosterman J.K.; Tseng J.-C.; Linden A.; *Siegel J.S. Towards the molecular Borromean link with three unequal rings: Double-threaded ruthenium(II) ring-in-ring complexes. Org. Chem. Front. 2016, 3(6), 667-672.      

101Stanek J.; Andreas L.B.; Jaudzems K.; Cala D.; Lalli D.; Bertarello A.; Schubeis T.; Akopjana I.; Kotelovica S.; Tars K.; Pica A.; Leone S.; Picone D.; Xu Z.-Q.; Dixon N.E.; Martinez D.; Berbon M.; El Mammeri N.; Noubhani A.; Saupe S.; Habenstein B.; Loquet A.; *Pintacuda G. NMR Spectroscopic Assignment of Backbone and Side-Chain Protons in Fully Protonated Proteins: Microcrystals, Sedimented Assemblies, and Amyloid Fibrils. Angew. Chem. Int. Ed. 2016, 55(50), 15504-15509.      

102Luginina J.; Rjabovs V.; *Stepanovs D. Crystal structure of 3-deoxy-3-nitromethyl-1,2;5,6-di-O-isopropylidene-α-d-allofuranose. Acta Crystallographica Section E: Crystallographic Communications 2016, 72, 314-317.      

103Dokane K.; Jonkus D.; Sjakste T. Evaluation of the RYR1 gene genetic diversity in the Latvian white pig breed. Bioplym. Cell 2016, 32(3), 184-189.      

104Rasiņa D.; Kahler-Quesada A.; Ziarelli S.; Warratz S.; Cao H.; Santoro S.; *Ackermann L.; Vaccaro L. Heterogeneous palladium-catalysed Catellani reaction in biomass-derived γ-valerolactone. Green Chem. 2016, 18(18), 5025-5030.      

105Tian X.; Yang F.; Rasiņa D.; Bauer M.; Warratz S.; Ferlin F.; *Vaccaro L.; Ackermann L. C-H arylations of 1,2,3-triazoles by reusable heterogeneous palladium catalysts in biomass-derived γ-valerolactone. Chem. Commun. 2016, 52(63), 9777-9780.      

106*Mihailovs I.; Kampars V.; Turovska B.; Rutkis M. Rational computing of energy levels for organic electronics: The case of 2-benzylidene-1,3-indandiones. RSC Adv. 2016, 6(88), 85242-85253.      

107*Leitis Z.; Lūsis V. Conjugate addition of aryl nucleophiles to α,β-unsaturated cinnamic acid derivatives containing Evans type chiral auxiliaries. Tetrahedron Asymmetry 2016, 27(17-18), 843-851.      

108Griniene R.; Liu L.; Tavgeniene D.; Sipaviciute D.; Volyniuk D.; Grazulevicius J.V.; Xie Z.; Zhang B.; Leduskrasts K.; *Grigalevicius S. Polyethers with pendent phenylvinyl substituted carbazole rings as polymers for hole transporting layers of OLEDs. Opt Mater 2016, 51, 148-153.      

109Bolsakova J.; *Jirgensons A. Synthesis of α-Ethynyl Glycines. Eur. J. Org. Chem. 2016, 2016(27), 4591-4602.      

110*Ošiņa K.; Rostoka E.; Sokolovska J.; Paramonova N.; Bisenieks E.; Duburs G.; Sjakste N.; Sjakste T. 1,4-Dihydropyridine derivatives without Ca2+-antagonist activity up-regulate Psma6 mRNA expression in kidneys of intact and diabetic rats. Cell Biochem. Funct. 2016, 34(1), 3-6.      

111*Velena A.; Zarkovic N.; Gall Troselj K.; Bisenieks E.; Krauze A.; Poikans J.; Duburs G. 1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues - Model Compounds Targeting Oxidative Stress. Oxidative Med. Cell. Longevity 2016, 2016.      

112*Traskovskis K.; Kokars V.; Tokmakovs A.; Mihailovs I.; Nitiss E.; Petrova M.; Belyakov S.; Rutkis M. Stereoselective synthesis and properties of 1,3-bis(dicyanomethylidene)indane-5-carboxylic acid acceptor fragment containing nonlinear optical chromophores. J. Mater. Chem. C 2016, 4(22), 5019-5030.      

113Beķere L.; Larina N.; Lokshin V.; Ellern A.; Sigalov M.; *Khodorkovsky V. A new class of spirocyclic photochromes reacting with light of both UV and visible ranges. New J. Chem. 2016, 40(8), 6554-6558.      

114*Batenko N.; Neibolte I.; Belyakov S.; Valters R. Synthesis, Characterization and Photophysical Properties of Naphtho[2,3-b]Indolizine-6,11-Dione Derivatives. J Fluoresc 2016, 26(1), 23-29.      

115Vasiļjeva J.; Domracheva I.; *Arsenyan P. Selenium analogues of (S)-clopidogrel: Preparation method and properties. Tetrahedron Lett. 2016, 57(2), 196-198.      

116Rasiņa D.; Otikovs M.; Leitans J.; Recacha R.; Borysov O.V.; Kanepe-Lapsa I.; Domračeva I.; Pantelejevs T.; Tars K.; Blackman M.J.; *Jaudzems K.; Jirgensons A. Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV. J. Med. Chem. 2016, 59(1), 374-387.      

117Sokolovs I.; *Suna E. Para-Selective Cu-Catalyzed C-H Aryloxylation of Electron-Rich Arenes and Heteroarenes. J. Org. Chem. 2016, 81(2), 371-379.      

118*Batenko N.; Kricka A.; Belyakov S.; Turovska B.; Valters R. A novel method for the synthesis of benzimidazole-based 1,4-quinone derivatives. Tetrahedron Lett. 2016, 57(3), 292-295.      

119Stepanovs D.; Tetere Z.; Rāviņa I.; Kumpins V.; Zicane D.; Bizdēna Ē.; Bogans J.; Novosjolova I.; Grigalovica A.; Meri R.M.; Fotins J.; Cerkasovs M.; Mishnev A.; *Turks M. Structural characterization of cevimeline and its trans-impurity by single crystal XRD. J. Pharm. Biomed. Anal. 2016, 118, 404-409.      

120Petuskovs A.; *Shubin K. Synthesis of 1,3-dihydro-2H-benzo[d]azepin-2-ones (microreview). Chem. Heterocycl. Compd. 2016, 52(2), 84-86.      

121*Grehov V.; Kalnacs J.; Mishnev A.; Kundzins K. Synthesis of Graphenic Carbon Materials on Nickel Particles with Controlled Quantity of Carbon. Latv. J. Phys. Tech. Sci. 2016, 53(1), 53-65.      

122Beķere L.; Lokshin V.; Sigalov M.; Gvishi R.; Zhao P.; Hagan D.J.; Van Stryland E.W.; *Khodorkovsky V. Chromenes involving a two-photon absorbing moiety: Photochromism via intramolecular resonance energy transfer. New J. Chem. 2016, 40(2), 1143-1148.      

123*Ābele E.; Belyakov S.; Beresņeva T.; Golomba L.; Abele R. Novel palladium-catalyzed domino reaction of 2-methylindoles with 2-iodobenzyl bromide. Chem. Heterocycl. Compd. 2016, 52(2), 140-142.      

124Nguyen T.T.; Grigorjeva L.; *Daugulis O. Cobalt-Catalyzed, Aminoquinoline-Directed Functionalization of Phosphinic Amide sp2 C-H Bonds. ACS Catal. 2016, 6(2), 551-554.      

125Kumpiņa I.; Isaksson R.; Savmarker J.; Wannberg J.; *Larhed M. Microwave Promoted Transcarbamylation Reaction of Sulfonylcarbamates under Continuous-Flow Conditions. Org. Process Res. Dev. 2016, 20(2), 440-445.      

126Stepanovs D.; Jure M.; Gosteva M.; Popelis J.; Kiseļovs G.; *Mishnev A. Crystal structures and physicochemical properties of diltiazem base and its acetylsalicylate, nicotinate and l-malate salts. Crystengcomm 2016, 18(7), 1235-1241.      

127Capligina V.; Bērziņa I.; Bormane A.; Salmane I.; Vilks K.; Kazarina A.; Bandere D.; Baumanis V.; *Ranka R. Prevalence and phylogenetic analysis of Babesia spp. in Ixodes ricinus and Ixodes persulcatus ticks in Latvia. Exp. Appl. Acarol. 2016, 68(3), 325-336.      

128Popova O.S.; *Bren' V.A.; Tkachev V.V.; Utenyshev A.N.; Revinskii Y.V.; Tikhomirova K.S.; Starikov A.G.; Borodkin G.S.; Dubonosov A.D.; Shilov G.V.; Aldoshin S.M.; Minkin V.I. Benzenoid-quinoid tautomerism of azomethines and their structural analogs 56. Azomethine imines, derivatives of salicylic and 2-hydroxynaphthoic aldehydes. Russ. Chem. Bull. 2016, 65(3), 648-653.      

129*Ukhin L.Y.; Shepelenko E.N.; Belousova L.V.; Popova O.S.; Alekseenko D.V. One-pot synthesis of cotarnine 1-alkynyl derivatives. Russ. Chem. Bull. 2016, 65(3), 831-833.      

130*Zarins A.; Valtenbergs O.; Kizane G.; Supe A.; Knitter R.; Kolb M.H.H.; Leys O.; Baumane L.; Conka D. Formation and accumulation of radiation-induced defects and radiolysis products in modified lithium orthosilicate pebbles with additions of titanium dioxide. J Nucl Mater 2016, 470, 187-196.      

131Hyde S.; Veliks J.; Liegault B.; Grassi D.; Taillefer M.; *Gouverneur V. Copper-Catalyzed Insertion into Heteroatom-Hydrogen Bonds with Trifluorodiazoalkanes. Angew. Chem. Int. Ed. 2016, 55(11), 3785-3789.      

132Ozols K.; Cīrule D.; Novosjolova I.; Stepanovs D.; Liepinsh E.; Bizdēna Ē.; *Turks M. Development of N6-methyl-2-(1,2,3-triazol-1-yl)-2′-deoxyadenosine as a novel fluorophore and its application in nucleotide synthesis. Tetrahedron Lett. 2016, 57(10), 1174-1178.      

133*Markovic D.; Tchawou W.A.; Novosjolova I.; Laclef S.; Stepanovs D.; Turks M.; Vogel P. Synthesis and Applications of Silyl 2-Methylprop-2-ene-1-sulfinates in Preparative Silylation and GC-Derivatization Reactions of Polyols and Carbohydrates. Chem. Eur. J. 2016, 22(12), 4196-4205.      

134Isaksson R.; Kumpiņa I.; Larhed M.; *Wannberg J. Rapid and straightforward transesterification of sulfonyl carbamates. Tetrahedron Lett. 2016, 57(13), 1476-1478.      

135Mierina I.; *Stepanovs D.; Kuginyte J.; Janichev A.; Jure M. Crystal structure of 3-(4-hydroxyphenyl)-2-[(E)-2- phenylethenyl]quinazolin-4(3H)-one. Acta Crystallographica Section E: Crystallographic Communications 2016, 72, 522-525.      

136*Sjakste T.; Paramonova N.; Ošiņa K.; Dokane K.; Sokolovska J.; Sjakste N. Genetic variations in the PSMA3, PSMA6 and PSMC6 genes are associated with type 1 diabetes in latvians and with expression level of number of UPS‑related and T1DM‑susceptible genes in HapMap individuals. Mol. Genet. Genomics 2016, 291(2), 891-903.      

137*Terentjeva S.; Muceniece D.; Petushkova J.; Lūsis V. Synthesis of novel 3-substituted benzamides related to imatinib. J. Chem. Res. 2016, 40(4), 224-227.      

138*Dambrova M.; Latkovskis G.; Kūka J.; Strele I.; Konrāde I.; Grinberga S.; Hartmane D.; Pugovičs O.; Erglis A.; Liepinsh E. Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels. Exp. Clin. Endocrinol. Diabetes 2016, 124(4), 251-256.      

139Sarceviča I.; Grante I.; Belyakov S.; Rekis T.; Bērziņš K.; Actins A.; *Orola L. Solvates of Dasatinib: Diversity and Isostructurality. J. Pharm. Sci. 2016, 105(4), 1489-1495.      

140*Smits R.; Turovska B.; Belyakov S.; Plotniece A.; Duburs G. Synthesis of 5-carboxy-6-methyl-3,4-dihydro-2(1H)-pyridone derivatives and their electrochemical oxidation to 2-pyridones. Chem. Phys. Lett. 2016, 649, 84-87.      

141Ivanovs I.; Bērziņa S.; Luginina J.; Belyakov S.; *Rjabovs V. Stereoselective Michael addition of O-nucleophiles to carbohydrate-based nitro-olefin. Heterocycl. Commun. 2016, 22(2), 95-98.      

142Gupta A.; Monteferrante C.; Rasiņa D.; Leitis G.; Randall C.P.; Tomlinson J.H.; Jirgensons A.; Goessens W.H.F.; Hays J.P.; *O'Neill A.J. A polymorphism in leuS confers reduced susceptibility to GSK2251052 in a clinical isolate of Staphylococcus aureus. Antimicrob. Agents Chemother. 2016, 60(5), 3219-3221.      

143*Liepinsh E.; Makrecka-Kuka M.; Volska K.; Kūka J.; Makarova E.; Antone U.; Sevostjanovs E.; Vilšķērsts R.; Strods A.; Tars K.; Dambrova M. Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem. J. 2016, 473(9), 1191-1202.      

144Massink A.; Louvel J.; Adlere I.; Van Veen C.; Huisman B.J.H.; Dijksteel G.S.; Guo D.; Lenselink E.B.; Buckley B.J.; Matthews H.; Ranson M.; Kelso M.; *Ijzerman A.P. 5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor. J. Med. Chem. 2016, 59(10), 4769-4777.      

145Mierina I.; Gudelis E.; *Stepanovs D.; Jure M.; Mishnev A.; Kolympadi M.; Markovic D. Crystal structure of 3-(4-hydroxy-3-methoxyphenyl)-N-phenylpropanamide, C16H17NO3. Z. Kristallograph. New Cryst. Struct. 2016, 231(2), 657-659.      

146*Krauze A.; Krasnova L.; Grīnberga S.; Sokolova E.; Domracheva I.; Shestakova I.; Duburs G. Synthesis of 6-alkylsulfanyl-1,4-dihydropyridines as potential multidrug resistance modulators. Heterocycl. Commun. 2016, 22(3), 157-160.      

147*Kharabayev N.N.; Popova O.S.; Bren D.V.; Minkin V.I. Azomethine imines of pyrazolidone series and their bis-chelate Ni(II), Zn(II), Cd(II) complexes. Quantum chemical simulation. Russ. J. Gen. Chem. 2016, 86(7), 1659-1663.      

148*Zviedre I.I.; Belyakov S.V. 2-Methyl-8-oxyquinolinium dicitratoborate dihydrate: Synthesis and crystal structure. Russ. J. Inorg. Chem. 2016, 61(7), 826-832.      

149*Leonova E.; Sokolovska J.; Boucher J.-L.; Isajevs S.; Rostoka E.; Baumane L.; Sjakste T.; Sjakste N. New 1,4-Dihydropyridines Down-regulate Nitric Oxide in Animals with Streptozotocin-induced Diabetes Mellitus and Protect Deoxyribonucleic Acid against Peroxynitrite Action. Basic Clin. Pharmacol. Toxicol. 2016, 119(1), 19-31.      

150*Arsenyan P.; Vasiļjeva J.; Belyakov S.; Petrova M.; Liepinsh E. Preparation and characterization of selenopheno[2,3-b]pyridine N-oxides. Mendeleev Commun. 2016, 26(4), 317-319.      

151Bluķe Z.; Paass E.; Sladek M.; Abel U.; *Kauss V. Synthesis of 3,4-dihydro-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxides and their evaluation as ligands for NMDA receptor glycine binding site. J. Enzyme Inhib. Med. Chem. 2016, 31(4), 664-673.      

152*Malina I.; Kampars V.; Turovska B. Synthesis, optical and electrochemical properties of substituted 2-cinnamoyl-1, 3-indandione O-methyl ethers. J. Mol. Struct. 2016, 1115, 241-249.      

153Paegle E.; Domracheva I.; Turovska B.; Petrova M.; Kanepe-Lapsa I.; Gulbe A.; Liepinsh E.; *Arsenyan P. Natural-Antioxidant-Inspired Benzo[b]selenophenes: Synthesis, Redox Properties, and Antiproliferative Activity. Chem. Asian J. 2016, 11(13), 1929-1938.      

154*Čerņaks D. Recent methods for the synthesis of indolizines (microreview). Chem. Heterocycl. Compd. 2016, 52(8), 524-526.      

155Priede M.; Priede E.; Saame J.; Leito I.; *Suna E. Synthesis of Chiral Phosphazene Bases. Chem. Heterocycl. Compd. 2016, 52(8), 541-545.      

156Petuskovs A.; *Shubin K. Synthesis of 1,2,4,5-tetrahydro-3H-2-benzazepin-3-one and related compounds (microreview). Chem. Heterocycl. Compd. 2016, 52(8), 530-532.      

157Pajuste K.; *Plotniece A. Ionic liquids, metal oxide nanoparticles, and enzymes in synthesis of 1,4-dihydropyridines (microreview). Chem. Heterocycl. Compd. 2016, 52(8), 538-540.      

158*Leitis Z. Synthesis of enantiomerically enriched 4-aryl-3,4-dihydrocoumarins (microreview). Chem. Heterocycl. Compd. 2016, 52(8), 527-529.      

159*Leduskrasts K. Routes to labeled tetrazoles (microreview). Chem. Heterocycl. Compd. 2016, 52(8), 533-534.      

160Tjernberg L.O.; *Rising A.; Johansson J.; Jaudzems K.; Westermark P. Transmissible amyloid. J. Intern. Med. (GBR) 2016, 280(2), 153-163.      

161*Ivanova J.; Žalubovskis R. Derivatives of 2-aziridinyl ketones and aziridinyl-2-carboxylates (microreview). Chem. Heterocycl. Compd. 2016, 52(8), 535-537.      

162Wang Y.; Romanovs V.; Spura J.; Ignatoviča L.; Roisnel T.; *Jouikov V. Anisyl-, aminophenyl-, and naphthylmethylsilatranes revisited. Chem. Heterocycl. Compd. 2016, 52(8), 546-550.      

163*Arsenyan P.; Rubina K.; Domracheva I. Synthesis and cytotoxicity of aminomethylselenopheno[3,2-b]thiophene sulfonamides. Chem. Heterocycl. Compd. 2016, 52(8), 555-558.      

164Domracheva I.; Gulbe A.; Paegle E.; *Arsenyan P. Selenium analogs of raloxifene: antioxidant activity endowed to an old drug. Chem. Heterocycl. Compd. 2016, 52(8), 551-554.      

165Andreas L.B.; Jaudzems K.; Stanek J.; Lalli D.; Bertarelloa A.; Marchand T.L.; De Paepe D.C.; Kotelovica S.; Akopjana I.; Knott B.; Wegner S.; Engelke F.; Lesage A.; Emsley L.; Tars K.; Herrmann T.; *Pintacuda G. Structure of fully protonated proteins by proton-detected magic- Angle spinning NMR. Proc. Natl. Acad. Sci. U. S. A. 2016, 113(33), 9187-9192.      

166*Recacha R.; Jaudzems K.; Akopjana I.; Jirgensons A.; Tars K. Crystal structure of Plasmodium falciparum proplasmepsin IV: The plasticity of proplasmepsins. Acta Crystallogr. Sect. F Struct. Biol. Commun. 2016, 72, 659-666.      

167Liepinsh E.; *Dambrova M. The unusual pharmacokinetics of meldonium: Implications for doping. Pharmacol. Res. 2016, 111, 100.      

168*Bērziņš K.; Kons A.; Grante I.; Dzabijeva D.; Nakurte I.; Actins A. Multi-technique approach for qualitative and quantitative characterization of furazidin degradation kinetics under alkaline conditions. J. Pharm. Biomed. Anal. 2016, 129, 433-440.      

169Randall C.P.; Rasiņa D.; Jirgensons A.; *O'Neill A.J. Targeting multiple aminoacyl-tRNA synthetases overcomes the resistance liabilities associated with antibacterial inhibitors acting on a single such enzyme. Antimicrob. Agents Chemother. 2016, 60(10), 6359-6361.      

170Shishovs M.; Rumnieks J.; Diebolder C.; Jaudzems K.; Andreas L.B.; Stanek J.; Kazaks A.; Kotelovica S.; Akopjana I.; Pintacuda G.; Koning R.I.; *Tars K. Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages. J. MOL. BIOL. 2016, 428(21), 4267-4279.      

171Popova O.S.; *Bren' V.A.; Tkachev V.V.; Utenyshev A.N.; Revinskii Y.V.; Tikhomirova K.S.; Rybalkin V.P.; Starikov A.G.; Borodkin G.S.; Dubonosov A.D.; Shilov G.V.; Aldoshin S.M.; Minkin V.I. Synthesis and structure of 1-[(3-hydroxybenzo[b]thiophen-2-yl)methylidene]-3-oxo-5-phenyl-1-pyrazolidinium-2-ide. Dokl. Chem. 2016, 471(1), 311-313.      

172*Romanchikova N.; Strods A.; Strazdina J.; Štrumfs B.; Trapencieris P. A novel aziridine-based bruton's tyrosine kinase inhibitor induces apoptosis through down-regulation of p65/RelA phosphorylation on serine 536 and ERK1/2 in mantle cell lymphoma. Anticancer Res. 2016, 36(11), 6133-6140.      

173*Jansone B.; Kadish I.; van Groen T.; Beitnere U.; Plotniece A.; Pajuste K.; Kluša V. Memory-enhancing and brain protein expression-stimulating effects of novel calcium antagonist in Alzheimer's disease transgenic female mice. Pharmacol. Res. 2016, 113, 781-787.      

174Monteferrante C.G.; Jirgensons A.; Varik V.; Hauryliuk V.; Goessens W.H.F.; *Hays J.P. Evaluation of the characteristics of leucyl-tRNA synthetase (LeuRS) inhibitor AN3365 in combination with different antibiotic classes. Eur. J. Clin. Microbiol. Infect. Dis. 2016, 35(11), 1857-1864.      

175*Ošiņa K.; Rostoka E.; Isajevs S.; Sokolovska J.; Sjakste T.; Sjakste N. Effects of an Antimutagenic 1,4-Dihydropyridine AV-153 on Expression of Nitric Oxide Synthases and DNA Repair-related Enzymes and Genes in Kidneys of Rats with a Streptozotocin Model of Diabetes Mellitus. Basic Clin. Pharmacol. Toxicol. 2016, 119(5), 458-463.      

176*Vāvers E.; Zvejniece L.; Švalbe B.; Volska K.; Makarova E.; Liepinsh E.; Rizhanova K.; Liepins V.; Dambrova M. The neuroprotective effects of R-phenibut after focal cerebral ischemia. Pharmacol. Res. 2016, 113, 796-801.      

177*Liepinsh E.; Makrecka-Kuka M.; Makarova E.; Volska K.; Švalbe B.; Sevostjanovs E.; Grinberga S.; Kūka J.; Dambrova M. Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance. Pharmacol. Res. 2016, 113, 788-795.      

178*Dambrova M.; Makrecka-Kuka M.; Vilšķērsts R.; Makarova E.; Kūka J.; Liepinsh E. Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity. Pharmacol. Res. 2016, 113, 771-780.      

179Aleksis R.; Jaudzems K.; Muceniece R.; *Liepinsh E. Lunasin is a redox sensitive intrinsically disordered peptide with two transiently populated α-helical regions. PEPTIDES 2016, 85, 56-62.      

180Zaharenko L.; Kalnina I.; Geldnere K.; Konrāde I.; Grinberga S.; Zidzik J.; Javorsky M.; Lejnieks A.; Nikitina-Zake L.; Fridmanis D.; Peculis R.; Radovica-Spalvina I.; Hartmane D.; Pugovičs O.; Tka I.; Klimakova L.; Pirags V.; *Klovins J. Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-Term response to metformin monotherapy in type 2 diabetes mellitus patients. Eur. J. Endocrinol. 2016, 175(6), 531-540.      

181*Dambrova M.; Liepinsh E. Response to comment by Sergei V. Jargin: “Meldonium (Mildronate): primum nоn nocere”. Pharmacol. Res. 2016, 114, 295-296.      

182*Ābele E.; Belyakov S.; Beresņeva T.; Golomba L.; Abele R. Novel palladium-catalyzed cascade reaction of 2-methylindoles with 2-iodobenzyl bromide leading to indole fused tricyclo[7,3,1,02,7]trideca-2(7),3,5-triene ring system. Curr. Org. Synth. 2016, 13(6), 883-887.      

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183Martjuga Marina; Scott L Dax; Ozola Vita; Suna Edgars; Mencel James Joseph; Shubin Kirill. Novel breathing control modulating compounds, and methods of using same. EP2968329, 20.01.2016.      

184Kalvins Ivars; Stonans Ilmars; Dambrova Maija; Liepins Edgars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... CN103608326, 20.01.2016.      

185Pugovics Osvalds; Dambrova Maija; Kuka Janis; Liepins Edgars; Loza Einars; Stonans Ilmars; Kalvins Ivars; Vilskersts Reinis; Andrianov Victor; Grinberga Solveiga; Gustina Daina; Lola Daina; Makrecka-Kuka Marina. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium or a pharmaceutically acceptable salt.... CU20150067, 29.01.2016.      

186Ozola Vita; Suna Edgars; Scott L Dax; Mannion James; Golder Francis John; Macintyre Duncan Euan; McLeod James; Shubin Kirill; Mencel James Joseph; Peng Sean. Novel orally bioavailable breathing control modulating compounds, and methods of using same. MX2015006120, 05.02.2016.      

187Martjuga Marina; Scott L Dax; Ozola Vita; Suna Edgars; Mencel James Joseph; Shubin Kirill. Novel breathing control modulating compounds, and methods of using same. US2016046635, 18.02.2016.      

188Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. AU2014292114, 18.02.2016.      

189Dambrova Maija; Liepins Edgars; Pugovics Osvalds; Vilskersts Reinis; Kuka Janis; Grinberga Solveiga; Loza Einars; Kalvins Ivars. Use of 4-[ethyl(dimethyl)ammonio]butanoate in the treatment of cardiovascular disease. US9278907, 08.03.2016.      

190Duburs Gunars; Kalnins Gints; Strods Arnis; Smits Rufs; Gulbe Anita; Shestakova Irina. Jauni savienojumi efektivai proteinu transfekcijai eikariotu sunas. LV15073, 20.03.2016.      

191Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. ES2566146, 11.04.2016.      

192Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. CN105518128, 20.04.2016.      

193Kalvins Ivars; Krauze Aivars; Krasnova Laura; Jaschenko Elina; Andzans Zigmars; Shestakova Irina; Duburs Gunars; Adlere Ilze; Domracheva Ilona. Thieno[2,3-b]pyridines as multidrug resistance modulators. EP3008073, 20.04.2016.      

194Pugovics Osvalds; Dambrova Maija; Kuka Janis; Liepins Edgars; Loza Einars; Stonans Ilmars; Kalvins Ivars; Vilskersts Reinis; Andrianov Victor; Grinberga Solveiga; Gustina Daina; Lola Daina; Makrecka-Kuka Marina. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium or a pharmaceutically acceptable salt.... MX2015008138, 25.04.2016.      

195Pugovics Osvalds; Dambrova Maija; Kuka Janis; Liepins Edgars; Loza Einars; Stonans Ilmars; Kalvins Ivars; Vilskersts Reinis; Andrianov Victor; Grinberga Solveiga; Gustina Daina; Lola Daina; Makrecka-Kuka Marina. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium or a pharmaceutically acceptable salt.... ZA201505093, 26.04.2016.      

196Kalvins Ivars; Stonans Ilmars; Dambrova Maija; Liepins Edgars; Cirule Helena; Misane Ilga; Makarova Elina. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium or pharmaceutically acceptable salt thereof.... CN105530929, 27.04.2016.      

197Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. EP2826856, 04.05.2016.      

198Martjuga Marina; Scott L Dax; Ozola Vita; Suna Edgars; Mencel James Joseph; Shubin Kirill. Novel breathing control modulating compounds, and methods of using same. MX2015013137, 05.05.2016.      

199Dambrova Maija; Liepins Edgars; Pugovics Osvalds; Vilskersts Reinis; Kuka Janis; Grinberga Solveiga; Loza Einars; Kalvins Ivars. Use of 4-[ethyl(dimethyl)ammonio]butanoate in the treatment of cardiovascular disease. US2016137589, 19.05.2016.      

200Kalvins Ivars; Cernobrovijs Aleksandrs; Lebedevs Antons. A method for preparation of erlotinib. GB2532620, 25.05.2016.      

201Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. EA201690232, 31.05.2016.      

202Stonans Ilmars; Dambrova Maija; Liepins Edgars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis; Kalvins Ivars. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... CY1117890, 08.06.2016.      

203Kalvins Ivars; Stonans Ilmars; Dambrova Maija; Liepins Edgars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... EP2702033, 08.06.2016.      

204Martjuga Marina; Scott L Dax; Ozola Vita; Suna Edgars; Mencel James Joseph; Shubin Kirill. Novel breathing control modulating compounds, and methods of using same. JP2016516714, 09.06.2016.      

205Zvejniece Liga; Dambrova Maija; Svalbe Baiba; Veinbergs Grigorijs; Vorona Maksims; Kalvins Ivars. Pharmaceutical composition for the prevention and treatment of inflammatory conditions. LV15129, 20.06.2016.      

206Kalvins Ivars; Stonans Ilmars; Dambrova Maija; Liepins Edgars; Cirule Helena; Misane Ilga; Makarova Elina. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium or pharmaceutically acceptable salt thereof.... MX2016003347, 24.06.2016.      

207Priepke Henning; Doods Henri; Kuelzer Raimund; Pfau Roland; Stenkamp Dirk; Pelcman Benjamin; Roenn Robert; Lubriks Dmitrijs; Suna Edgars. 2-(Arylamino)-3H-imidazo[4,5-b]pyridine-6-carboxamide derivatives and their use as MPGES-1 .... BR112013003843, 28.06.2016.      

208Kalvins Ivars; Stonans Ilmars; Dambrova Maija; Liepins Edgars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... EA023547, 30.06.2016.      

209Kalvins Ivars; Veinbergs Grigorijs; Vorona Maksims; Zvejniece Liga; Cernobrovijs Aleksandrs; Karina Ligita; Dambrova Maija. Method of preparation and use of pharmacologically active N-carbamoylmethyl-4(R)-phenyl-2-pyrroli.... US9382203, 05.07.2016.      

210Kalvins Ivars; Lebedevs Antons; Zvejniece Liga; Dambrova Maija; Svalbe Baiba; Liepins Edgars; Cernobrovijs Aleksandrs; Varaceva Larisa. Pharmaceutical composition for controlling body mass gain comprising S-phenotropil. DE112014004843, 07.07.2016.      

211Pfau Roland; Arndt Kirsten; Doods Henri; Klinder Klaus; Kuelzer Raimund; Lubriks Dmitrijs; Mack Juergen; Pelcman Benjamin; Priepke Henning; Roenn Robert; Stenkamp Dirk; Suna Edgars. 3H-imidazo[4,5-c]pyridine-6-carboxamides as anti inflammatory agents. AU2010220263, 14.07.2016.      

212Suna Edgars; Mutule Ilga; Berzina Beatrise. Hydropalladium(II) halides as preformed catalysts for Suzuki-Miyaura cross-coupling reactions. DE112013007541, 21.07.2016.      

213Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. MX2016000462, 26.07.2016.      

214Kalvins Ivars; Stonans Ilmars; Dambrova Maija; Liepins Edgars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... AU2012247467, 28.07.2016.      

215Wikberg Jarl; Jirgensons Aigars; Liepins Edvards. Phragmalin limonoids for the treatment of sexual dysfunction. US9403841, 02.08.2016.      

216Wikberg Jarl; Liepins Edvards; Jirgensons Aigars. Novel compounds, their manufacture and uses (II). US9403841, 02.08.2016.      

217Kalvins Ivars; Jirgensons Aigars; Domracheva Ilona; Kanepe-Lapsa Iveta; Rasina Dace; Jaudzems Kristaps; Otikovs Martins. Novel substituted 2-aminoquinazolin-4(3H)-one derivates as malarial aspartic protease inhibitors. DE112013007543, 04.08.2016.      

218Kalvins Ivars; Stonans Ilmars; Dambrova Maija; Liepins Edgars; Cirule Helena; Misane Ilga; Makarova Elina. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium or pharmaceutically acceptable salt thereof.... AR099638, 10.08.2016.      

219Kalvins Ivars; Lebedevs Antons; Cernobrovijs Aleksandrs. A process for the preparation of lenalidomide. GB2535004, 10.08.2016.      

220Jirgensons Aigars; Loza Einars; William Finn Paul; Charlton Michael; Ribas de Pouplana Lluis; Saint-Leger Adelaide. Novel N-acyl-diarylsulfonamide derivatives as aminoacyl t-RNA synthetase inhibitors. WO2016129983, 18.08.2016.      

221Jirgensons Aigars; Loza Einars; William Finn Paul; Charlton Michael; Ribas de Pouplana Lluis; Saint-Leger Adelaide. Novel N-acyl-diarylsulfonamide derivatives as aminoacyl t-RNA synthetase inhibitors. CA2975682, 18.08.2016.      

222Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... DK2702033, 29.08.2016.      

223Kalvins Ivars; Lebedevs Antons; Zvejniece Liga; Dambrova Maija; Svalbe Baiba; Liepins Edgars; Cernobrovijs Aleksandrs; Varaceva Larisa. Pharmaceutical composition for controlling body mass gain comprising S-phenotropil. US2016250185, 01.09.2016.      

224Stonans Ilmars; Dambrova Maija; Liepins Edgars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis; Kalvins Ivars. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... LT2702033, 12.09.2016.      

225Zvejniece Liga; Dambrova Maija; Veinbergs Grigorijs; Vorona Maksims; Kalvins Ivars. Pharmaceutical composition for the prevention and treatment of diseases associated with elevated.... LV15072, 20.09.2016.      

226Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... JP5997762, 28.09.2016.      

227Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. JP2016529886, 29.09.2016.      

228Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... SI2702033, 30.09.2016.      

229Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... TN2015000236, 03.10.2016.      

230Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... ES2585558, 06.10.2016.      

231Arsenjans Pavels; Vasiljeva Jelena; Domracheva Ilona; Shestakova Irina; Gulbe Anita; Kanepe-Lapsa Iveta; Kauss Valerjans; Kalvins Ivars. Ethynylxanthines, preparation and use as calcium ion channel modulators. WO2016159747, 06.10.2016.      

232Arsenjans Pavels; Vasiljeva Jelena; Domracheva Ilona; Shestakova Irina; Gulbe Anita; Kanepe-Lapsa Iveta; Kauss Valerjans; Kalvins Ivars. Novel ethynylxanthines, their preparation and use as inhibitors of matrix metalloproteinases and.... WO2016159746, 06.10.2016.      

233Arsenjans Pavels; Vasiljeva Jelena; Domracheva Ilona; Shestakova Irina; Gulbe Anita; Kanepe-Lapsa Iveta; Kauss Valerjans; Kalvins Ivars. Ethynylxanthines, preparation and use for cancer treatment. CA2989161, 06.10.2016.      

234Arsenjans Pavels; Vasiljeva Jelena; Domracheva Ilona; Shestakova Irina; Gulbe Anita; Kanepe-Lapsa Iveta; Kauss Valerjans; Kalvins Ivars. Ethynylxanthines, preparation and use for cancer treatment. WO2016159745, 06.10.2016.      

235Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Grinberga Solveiga; Loza Einars; Kuka Janis; Lola Daina; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... HRP20160998, 21.10.2016.      

236Erchak Nikolai; Kalvins Ivars; Belyakov Sergey; Malgorzata Zielonka; Liepins Edvards; Arsenjans Pavels; Olszewska Ewa. Method for preparing N-morpholiniomethylspirobe(2,5-dioxa-3oxo-1-silacyclopentan)ate. PL223545, 31.10.2016.      

237Wikberg Jarl; Jirgensons Aigars; Liepins Edvards. Phragmalin limonoids for the treatment of sexual dysfunction. NZ626736, 25.11.2016.      

238Kalvins Ivars; Lebedevs Antons; Cernobrovijs Aleksandrs; Dambrova Maija; Zvejniece Liga; Vorona Maksims; Veinbergs Grigorijs. 4R,5S-enantiomer of 2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide with nootropic activity. CY1114881, 14.12.2016.      

239Jirgensons Aigars; Loza Einars; William Finn Paul; Charlton Michael; Ribas de Pouplana Lluis; Saint-Leger Adelaide. N-acyl-diarylsulfonamide derivatives as aminoacyl t-RNA synthetase inhibitors. LV15146, 20.12.2016.      

240Kalvins Ivars; Dambrova Maija; Liepins Edgars; Stonans Ilmars. 4-[(Haloalkyl)dimethyl)ammonio]butanoates and use thereof in the treatment of cardiovascular.... BR112013027075, 27.12.2016.      

241Stonans Ilmars; Dambrova Maija; Liepins Edgars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis; Kalvins Ivars. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... BR112013027065, 27.12.2016.      

242Venskus Dite; Kalvins Ivars; Pjanova Dace; Petrovska Ramona; Auzins Jurgis. Genetically stable oncolytic RNA virus, method of manufacturing and use thereof. US2016376562, 29.12.2016.      

243Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Grinberga Solveiga; Kuka Janis; Lola Daina; Loza Einars; Pugovics Osvalds; Vilskersts Reinis. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... RS55092, 30.12.2016.      

Other publications
244*Jirgensons A.; Skvorcova M. Allylic Amination via Acid Catalyzed Leaving Group Activation. Curr.Med.Chem. 2016, 3(2), 145-149.      

245Carstensen E.; Loža E.; Finn P.W. The Discovery and Development of Belinostat. In Successful Drug Discovery. Fischer J., Childers W. E., Eds.,. Wiley-VCH 2016, 2, 31-58.      

246Golomba L.; Abele R.; *Abele E. Scope and mechanism of Cu-catalyzed reactions of 2-aminobenzothiazole and 1-benzyl-2-aminobenzoimidazole with 1-bromo-2-iodobenzene. Heterocyclic Letters 2016, 6(1), 57-60.      

247Петухов В.И.; Дмитриев Е.В.; Баумане Л.Х.; Скальный A.B.; Лобанова Ю.Н. ЭЛЕКТРОГЕННЫЕ МЕТАЛЛЫ В ЭПИДЕРМИСЕ: СВЯЗЬ С БИОЭНЕРГЕТИКОЙ КЛЕТКИ, Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской Академии медицинских наук. 2016, 3 (109), Часть 2, 58-64.      

248Petuhovs V.; Dmitriev E.V.; Baumane L.Kh.; Skalny A.V.; Lobanova Yu. N. Electrogenic Metals in Epidermis: Relationship with Cell Bioenergetics, Insights in Biomedicine (http://www.medpub.com). 2016, 1(2:9), 1-6.      

249Петухов В.И.; Дмитриев Е.В.; Баумане Л.Х.; Скальный A.B.; Лобанова Ю.Н. Электрогенные металлы в клетках эптдермиса: синхронизация (критичность) работы мембранных АТРаз. Международная научная конференция Двенадцатый съезд Белорусского общественного объединения фотобиологов и биофизиков. Минск, 28-30 июня. 2016, 170-173.      

250Скальный A.B.; Баумане Л.Х.; Дмитриев Е.В.; Петухов В.И. Гомеостаз электрогенных металлов в эпидермисе как явление самоорганизованной критичности (http://www.glorioz.com/doki/me/2016/ME_2016.pdf). IT+M&Ec`2016, Гурзуф, 02 - 12 июня. 2016, 191-194.      

251Petricenko O.; Pajuste K.; Plotniece A.; Cebers A. ; Ruciņš M. Dependence of magnetic liposomes formation applying phase-evaporation method on the structure of pyridinium amphiphiles. Proceeding the 10th International PAMIR Conference on Fundamental and Applied MHD, Cagliari, Italy, June 5-9. 2016, 466-470.