Pharmacomodulators synthesis group

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Dr. chem. Pavel Arsenyan
Group leader
e-mail: 
Phone: (+371) 29849464

Organic synthesis, chemistry of selenium and tellurium and antitumor activity investigations, development of new methods in heterocyclic chemistry, organometallic chemistry, transition metal and phase transfer catalysis, elaboration of eco-friendly synthetic methods.

Recent publications

  1. Arsenyan P.; Petrenko A.; Belyakov S. Improved conditions for the synthesis and transformations of aminomethyl selenophenothiophenes. Tetrahedron 2015, 71, 2226-2233.
  2. Arsenyan P.; Vasiljeva J.; Shestakova I.; Domracheva I.; Jaschenko E.; Romanchikova N.; Leonchik A.; Rudevica Z.; Belyakov S. Selenopheno[3,2-c]- and [2,3-c]coumarins: synthesis, cytotoxicity, angiogenesis inhibition, and antioxidant properties. Comptes Rendus Chimie. 2015, 18, 399-409.
  3. Arsenyan P. A simple method for the preparation of selenopheno[3,2-b] and [2,3-b]thiophenes. Tetrahedron Lett. 2014, 55, 2527-2529
  4. Paegle E.; Belyakov S.; Arsenyan P. An approach to the selenobromination of aryl(thienyl)alkynes: Access to 3-bromobenzo[b]selenophenes and selenophenothiophenes. J. Org. Chem. 2014, 3831-3840.
  5. Arsenyan P.; Paegle E.; Domracheva I.; Gulbe A.; Kanepe-Lapsa I.; Shestakova I. Selenium analogues of raloxifene as promising antiproliferative agents in treatment of breast cancer. Eur. J. Med. Chem. 2014, 87, 471-483.